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The antibody against HK3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HK3 (NP_002106.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against HK3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HK3 (NP_002106.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-12072A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HK3 |
| Target Synonyms | HXK3; HKIII; HK3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, HL-60, Mouse liver, NCI-H460, THP-1 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human HK3 (NP_002106.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P52790 | Immunogen Sequence |
Uniprot Id
P52790
Target Species
Human
Target Name
HK3
Target Full Name
Hexokinase-3
Target Function
Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate.
Target Protein Families
Hexokinase family
Target Synonyms
ATP:D hexose 6 phosphotransferase; Hexokinase type III; Hexokinase-3; Hexokinase3; HK III; Hk3; HKIII; HXK3; HXK3_HUMAN
Target Background
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.
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