Rabbit anti-Human HKDC1 Polyclonal Antibody

Uniprot Id

Q2TB90

Target Species

Human

Target Name

HKDC1

Target Full Name

Hexokinase HKDC1

Target Function

Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases. Has low glucose phosphorylating activity compared to other hexokinases. Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role.

Target Subcellular Location

Mitochondrion membrane; Peripheral membrane protein.

Target Protein Families

Hexokinase family

Target Tissue Specificity

Widely expressed. Highly expressed in the brush border, surface epithelium and the myenteric plexus of the small and large intestines; the acinar centrocytes and interlobular ducts of the pancreas; and the alveolar macrophages in the lungs (at protein lev

Target Synonyms

BC016235; Hexokinase domain containing 1; Hexokinase domain-containing protein 1; Hkdc1; HKDC1_HUMAN; Putative hexokinase HKDC1

Target Background

This gene encodes a member of the hexokinase protein family. The encoded protein is involved in glucose metabolism, and reduced expression may be associated with gestational diabetes mellitus. High expression of this gene may also be associated with poor prognosis in hepatocarcinoma.