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The antibody against INPP5J was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 60-360 of human INPP5J (NP_001002837.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against INPP5J was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 60-360 of human INPP5J (NP_001002837.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-02919A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | INPP5J |
| Target Synonyms | PIPP; INPP5; PIB5PA; INPP5J | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, A375 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 60-360 of human INPP5J (NP_001002837.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q15735 | Immunogen Sequence |
Uniprot Id
Q15735
Target Species
Human
Target Name
INPP5J
Target Full Name
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
Target Function
Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Inositol 1,4,5-trisphosphate 5-phosphatase type II family
Target Synonyms
INPP5J; PIB5PA; PIPP; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; EC 3.1.3.56; Inositol polyphosphate 5-phosphatase J
Target Background
Predicted to enable phosphatidylinositol-3, 4, 5-trisphosphate 5-phosphatase activity and phosphatidylinositol-4, 5-bisphosphate 5-phosphatase activity. Predicted to be involved in inositol phosphate dephosphorylation; negative regulation of peptidyl-serine phosphorylation; and phosphatidylinositol dephosphorylation. Predicted to act upstream of or within negative regulation of neuron projection development. Located in cytoplasm and ruffle.
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