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The antibody against ISYNA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ISYNA1 (NP_057452.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ISYNA1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ISYNA1 (NP_057452.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01076A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ISYNA1 |
| Target Synonyms | IPS; INO1; INOS; IPS 1; IPS-1; ISYNA1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ISYNA1 (NP_057452.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NPH2 | Immunogen Sequence |
Uniprot Id
Q9NPH2
Target Species
Human
Target Name
ISYNA1
Target Full Name
Inositol-3-phosphate synthase 1
Target Function
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Myo-inositol 1-phosphate synthase family
Target Tissue Specificity
Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.
Target Synonyms
hINO1; hIPS; INO1; INO1_HUMAN; INOS; Inositol 3 phosphate synthase 1; Inositol-3-phosphate synthase 1; IPS ; IPS 1; ISYNA 1; Isyna1; MI 1 P synthase; MI-1-P synthase; MI1P synthase; MIP synthase; Myo inositol 1 phosphate synthase A1; Myo-inositol 1-phosphate synthase A1; Myo-inositol-1-phosphate synthase
Target Background
This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4.
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