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The antibody against KCNU1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 920-1149 of human KCNU1 (NP_001027006.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against KCNU1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 920-1149 of human KCNU1 (NP_001027006.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11403A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KCNU1 |
| Target Synonyms | KCa5; Slo3; KCNMC1; KCa5.1; Kcnma3; SPGF79; KCNU1 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 920-1149 of human KCNU1 (NP_001027006.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | A8MYU2 | Immunogen Sequence |
Uniprot Id
A8MYU2
Target Species
Human
Target Name
KCNU1
Target Full Name
Potassium channel subfamily U member 1
Target Function
Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). May represent the primary spermatozoan K(+) current. In contrast to KCNMA1/SLO1, it is not activated by Ca(2+) or Mg(2+). Critical for fertility. May play an important role in sperm osmoregulation required for the acquisition of normal morphology and motility when faced with osmotic challenges, such as those experienced after mixing with seminal fluid and entry into the vagina.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Potassium channel family, Calcium-activated (TC 1.A.1.3) subfamily, KCa5.1/KCNU1 sub-subfamily
Target Tissue Specificity
Testis-specific.
Target Synonyms
subfamily M subunit alpha-3; Calcium activated potassium channel subfamily M subunit alpha 3; Calcium activated potassium channel subunit alpha 3; Calcium-activated potassium channel; Calcium-activated potassium channel subunit alpha-3; KCa5; KCa5.1; Kcnma3; KCNMC1; KCNU 1; KCNU1; KCNU1_HUMAN; Potassium channel subfamily U member 1; Slo3; Slowpoke homolog 3
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