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Rabbit anti-Human LSM2 Polyclonal Antibody

The antibody against LSM2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human LSM2 (NP_067000.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00038A

The antibody against LSM2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human LSM2 (NP_067000.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-00038A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLSM2
Target SynonymsG7B; snRNP; C6orf28; YBL026W; LSM2FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesSKOV3, SW620ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human LSM2 (NP_067000.1).Target SpeciesHuman
Immunogen SequenceMLFYSFFKSLVGKDVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPEKYPHMLSVKNCFIRGSVVRYVQLPADEVDTQLLQDAARKEALQQKQUniprot IDQ9Y333
Background Information
  • Uniprot Id

    Q9Y333

  • Target Species

    Human

  • Target Name

    LSM2

  • Target Full Name

    U6 snRNA-associated Sm-like protein LSm2

  • Target Function

    Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    SnRNP Sm proteins family

  • Target Synonyms

    G7B; snRNP; C6orf28; YBL026W; LSM2

  • Target Background

    This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19.

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