Rabbit anti-Human MEF2B Polyclonal Antibody

Uniprot Id

Q02080

Target Species

Human

Target Name

MEF2B

Target Full Name

Myocyte-specific enhancer factor 2B

Target Function

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.

Target Subcellular Location

Nucleus.

Target Protein Families

MEF2 family

Target Tissue Specificity

Expressed in skeletal and cardiac muscle and brain.

Target Synonyms

RSRFR2; MEF2B

Target Background

The product of this gene is a member of the MADS/MEF2 family of DNA binding proteins. The protein is thought to regulate gene expression, including expression of the smooth muscle myosin heavy chain gene. This region undergoes considerable alternative splicing, with transcripts supporting two non-overlapping loci (GeneID 729991 and 100271849) as well as numerous read-through transcripts that span both loci (annotated as GeneID 4207). Several isoforms of this protein are expressed from either this locus or from some of the read-through transcripts annotated on GeneID 4207.