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The antibody against MPP6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human MPP6 (NP_057531.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MPP6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human MPP6 (NP_057531.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06423A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MPP6 |
| Target Synonyms | MPP6; VAM1; p55T; VAM-1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, 293T, K-562, Mouse brain, Mouse liver, SW480 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human MPP6 (NP_057531.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NZW5 | Immunogen Sequence |
Uniprot Id
Q9NZW5
Target Species
Human
Target Name
PALS2
Target Full Name
Protein PALS2
Target Subcellular Location
Membrane; Peripheral membrane protein.
Target Protein Families
MAGUK family
Target Tissue Specificity
Abundant in testis, brain, and kidney with lower levels detectable in other tissues.
Target Synonyms
MAGUK p55 subfamily member 6; MAGUK p55 subfamily member 6 VELI associated MAGUK 1; MAGUK protein p55T; Membrane protein palmitoylated 6; Mpp6; MPP6_HUMAN; p55T; Palmitoylated 6 MAGUK p55 subfamily member 6; PALS2; Protein associated with Lin7 2; VAM-1; VELI associated MAGUK 1; Veli-associated MAGUK 1
Target Background
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).
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