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The antibody against MPP7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human MPP7 (NP_775767.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MPP7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human MPP7 (NP_775767.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00162A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MPP7 |
| Target Synonyms | MPP7 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human MPP7 (NP_775767.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q5T2T1 | Immunogen Sequence |
Uniprot Id
Q5T2T1
Target Species
Human
Target Name
MPP7
Target Full Name
MAGUK p55 subfamily member 7
Target Function
Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.
Target Subcellular Location
Membrane; Peripheral membrane protein. Lateral cell membrane; Peripheral membrane protein. Cell junction, tight junction. Cell junction, adherens junction. Cytoplasm, cell cortex. Cytoplasm.
Target Protein Families
MAGUK family
Target Synonyms
FLJ32798; MAGUK p55 subfamily member 7; Membrane protein palmitoylated 7 MAGUK p55 subfamily member 7; MPP7; MPP7_HUMAN; Palmitoylated membrane protein 7
Target Background
The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in this gene are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants.
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