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The antibody against MRPL44 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 31-332 of human MRPL44 (NP_075066.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MRPL44 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 31-332 of human MRPL44 (NP_075066.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09728A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL44 |
| Target Synonyms | L44MT; COXPD16; MRP-L44; MRPL44 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 31-332 of human MRPL44 (NP_075066.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H9J2 | Immunogen Sequence |
Uniprot Id
Q9H9J2
Target Species
Human
Target Name
MRPL44
Target Full Name
Large ribosomal subunit protein mL44
Target Function
Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome.
Target Involvement
Combined oxidative phosphorylation deficiency 16 (COXPD16)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Ribonuclease III family, Mitochondrion-specific ribosomal protein mL44 subfamily
Target Synonyms
MRPL44; 39S ribosomal protein L44; mitochondrial; L44mt; MRP-L44; EC 3.1.26.-; Mitochondrial large ribosomal subunit protein mL44
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
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