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The antibody against MRPL46 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-279 of human MRPL46 (NP_071446.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against MRPL46 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-279 of human MRPL46 (NP_071446.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-05066A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPL46 |
| Target Synonyms | LIECG2; P2ECSL; C15orf4; MRPL46 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HAP1, Mouse brain, Rat thymus, Rat uterus | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-279 of human MRPL46 (NP_071446.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9H2W6 | Immunogen Sequence |
Uniprot Id
Q9H2W6
Target Species
Human
Target Name
MRPL46
Target Full Name
Large ribosomal subunit protein mL46
Target Subcellular Location
Mitochondrion.
Target Protein Families
Mitochondrion-specific ribosomal protein mL46 family
Target Synonyms
39S ribosomal protein L46; 39S ribosomal protein L46 mitochondrial; C15orf4; L46mt; LIECG 2; LIECG2; MGC22762; mitochondrial; Mitochondrial ribosomal protein L46; MRP L46; MRP-L46; MRPL 46; Mrpl46; P2ECSL; RM46_HUMAN
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
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