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The antibody against MRPS23 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 1-190 of human MRPS23 (NP_057154.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against MRPS23 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 1-190 of human MRPS23 (NP_057154.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-08483A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MRPS23 |
| Target Synonyms | CGI-138; COXPD46; HSPC329; MRP-S23; MRPS23 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Hep G2, MCF7 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant Protein corresponding to a sequence within amino acids 1-190 of human MRPS23 (NP_057154.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MAGSRLETVGSIFSRTRDLVRAGVLKEKPLWFDVYDAFPPLREPVFQRPRVRYGKAKAPIQDIWYHEDRIRAKFYSVYGSGQRAFDLFNPNFKSTCQRFVEKYTELQKLGETDEEKLFVETGKALLAEGVILRRVGEARTQHGGSHVSRKSEHLSVRPQTALEENETQKEVPQDQHLEAPADQSKGLLPP | Uniprot ID | Q9Y3D9 |
Uniprot Id
Q9Y3D9
Target Species
Human
Target Name
MRPS23
Target Full Name
Small ribosomal subunit protein mS23
Target Involvement
Defects in MRPS23 may play a role in mitochondrial disorders characterized by combined respiratory chain complex deficiencies.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Mitochondrion-specific ribosomal protein mS23 family
Target Synonyms
CGI-138; COXPD46; HSPC329; MRP-S23; MRPS23
Target Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p.
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