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Rabbit anti-Human NUTF2 Polyclonal Antibody

The antibody against NUTF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human NUTF2 (NP_005787.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09386A

The antibody against NUTF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human NUTF2 (NP_005787.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09386A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNUTF2
Target SynonymsNTF2; PP15; NTF-2; NUTF2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse heartApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human NUTF2 (NP_005787.1).Target SpeciesHuman
Immunogen SequenceMGDKPIWEQIGSSFIQHYYQLFDNDRTQLGAIYIDASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSITAQDHQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNFGUniprot IDP61970
Background Information
  • Uniprot Id

    P61970

  • Target Species

    Human

  • Target Name

    NUTF2

  • Target Full Name

    Nuclear transport factor 2

  • Target Function

    Mediates the import of GDP-bound RAN from the cytoplasm into the nucleus which is essential for the function of RAN in cargo receptor-mediated nucleocytoplasmic transport. Thereby, plays indirectly a more general role in cargo receptor-mediated nucleocytoplasmic transport. Interacts with GDP-bound RAN in the cytosol, recruits it to the nuclear pore complex via its interaction with nucleoporins and promotes its nuclear import.

  • Target Subcellular Location

    Cytoplasm, cytosol. Nucleus outer membrane. Nucleus, nuclear pore complex. Nucleus inner membrane. Nucleus, nucleoplasm.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    NTF 2; NTF-2; NTF2; NTF2_HUMAN; Nuclear transport factor 2; Nutf2; Placental protein 15; PP15

  • Target Background

    This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62.

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