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Rabbit anti-Human P2RY11 Polyclonal Antibody

The antibody against P2RY11 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300-379 of human P2RY11 (NP_002557.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04116A

The antibody against P2RY11 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300-379 of human P2RY11 (NP_002557.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04116A ClonalityPolyclonal
Host SpeciesRabbitTarget NameP2RY11
Target SynonymsP2Y11; P2RY11FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse liver, Rat liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 300-379 of human P2RY11 (NP_002557.2).Target SpeciesHuman
Immunogen SequenceYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQUniprot IDQ96G91
Background Information
  • Uniprot Id

    Q96G91

  • Target Species

    Human

  • Target Name

    P2RY11

  • Target Full Name

    P2Y purinoceptor 11

  • Target Function

    Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Highest expression in liver and spleen.

  • Target Synonyms

    P2RY11; P2Y purinoceptor 11; P2Y11

  • Target Background

    The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product.

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