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The antibody against PD-L2 was raised in mouse using the Recombinant Human Programmed cell death 1 ligand 2 protein (21-118AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG2b, purified by protein A with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF, FC, IP.
The antibody against PD-L2 was raised in mouse using the Recombinant Human Programmed cell death 1 ligand 2 protein (21-118AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG2b, purified by protein A with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF, FC, IP.
$350.00
Western Blot_x000D_ | Positive WB detected in: HepG2 whole cell lysate, Hela whole cell lysate, PC-3 whole cell lysate, A549 whole cell lysate _x000D_ | All lanes PD-L2 antibody at 1:2000_x000D_ | Secondary_x000D_ | Goat polyclonal to mouse IgG at 1/50000 dilution_x000D_ | Predicted band size: 31,21 KDa_x000D_ | Observed band size: 45-50 KDa_x000D_ | Exposure time:5min
| Cat.No | ADC-55436A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Mouse | Target Name | PD-L2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG2b | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein A purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB, FC, IP | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Programmed cell death 1 ligand 2 protein (21-118AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BQ51 |
Uniprot Id
Q9BQ51
Target Species
Human
Target Name
PDCD1LG2
Target Full Name
Programmed cell death 1 ligand 2
Target Function
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Target Subcellular Location
[Isoform 3]: Secreted.; [Isoform 2]: Endomembrane system; Single-pass type I membrane protein.; [Isoform 1]: Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, BTN/MOG family
Target Tissue Specificity
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Target Research Area
Immunology
Target Synonyms
B7 dendritic cell molecule; B7-DC; B7DC; bA574F11.2; Btdc; Butyrophilin B7 DC; Butyrophilin B7-DC; Butyrophilin B7DC ; CD 273; CD273; CD273 antigen ; MGC142238; MGC142240; PD 1 ligand 2; PD L2; PD-1 ligand 2; PD-L2; PD1 ligand 2; PD1L2_HUMAN; PDCD 1 ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; PDL 2; PDL2; Programmed cell death 1 ligand 2; Programmed death ligand 2
Target Background
Involved in negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; and negative regulation of interleukin-10 production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Biomarker of pulmonary tuberculosis.
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