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The antibody against PDE3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human PDE3B (NP_000913.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PDE3B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human PDE3B (NP_000913.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09013A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDE3B |
| Target Synonyms | HcGIP1; cGIPDE1; PDE3B | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, LO2, Mosue liver, SW620 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human PDE3B (NP_000913.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q13370 | Immunogen Sequence |
Uniprot Id
Q13370
Target Species
Human
Target Name
PDE3B
Target Full Name
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
Target Function
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Cyclic nucleotide phosphodiesterase family, PDE3 subfamily
Target Tissue Specificity
Abundant in adipose tissues.
Target Synonyms
5''-cyclic phosphodiesterase B; Adipocyte cAMP phosphodiesterase cGMP inhibited; AI847709; cAMP Phosphodiesterase, adipocyte, cGMP-inhibited; CGI-PDE B; CGIP1; CGIPDE B; CGIPDE1; cGMP inhibited 3 5 cyclic phosphodiesterase B; CGMP inhibited cAMP phophodiesterase; cGMP-inhibited 3''; Cyclic GMP inhibited phosphodiesterase B; Cyclic GMP-inhibited phosphodiesterase B; Cyclic nucleotide phosphodiesterase; HcGIP1; HcGIP1, rat, homolog of; Pde3b; PDE3B_HUMAN; Phosphodiesterase 3B; Phosphodiesterase 3B cGMP inhibited
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