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The antibody against PEX16 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 132-336 of human PEX16 (NP_004804.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PEX16 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 132-336 of human PEX16 (NP_004804.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09050A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PEX16 |
| Target Synonyms | PBD8A; PBD8B; PEX16 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-549, HT-1080, MCF7, SW620 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 132-336 of human PEX16 (NP_004804.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y5Y5 | Immunogen Sequence |
Uniprot Id
Q9Y5Y5
Target Species
Human
Target Name
PEX16
Target Full Name
Peroxisomal membrane protein PEX16
Target Function
Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Can recruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmic reticulum (ER). May function as receptor for PEX3.
Target Involvement
Peroxisome biogenesis disorder complementation group 9 (PBD-CG9); Peroxisome biogenesis disorder 8A (PBD8A); Peroxisome biogenesis disorder 8B (PBD8B)
Target Subcellular Location
Peroxisome membrane; Multi-pass membrane protein.
Target Protein Families
Peroxin-16 family
Target Synonyms
PEX16; Peroxisomal membrane protein PEX16; Peroxin-16; Peroxisomal biogenesis factor 16
Target Background
The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.
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