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The antibody against PPM1G was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 297-546 of human PPM1G (NP_817092.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PPM1G was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 297-546 of human PPM1G (NP_817092.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02220A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PPM1G |
| Target Synonyms | PP2CG; PPP2CG; PP2CGAMMA; PPM1G | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-431, Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 297-546 of human PPM1G (NP_817092.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O15355 | Immunogen Sequence |
Uniprot Id
O15355
Target Species
Human
Target Name
PPM1G
Target Full Name
Protein phosphatase 1G
Target Subcellular Location
Cytoplasm. Membrane; Lipid-anchor.
Target Protein Families
PP2C family
Target Tissue Specificity
Widely expressed. Most abundant in testis, skeletal muscle, and heart.
Target Synonyms
MGC1675; MGC2870; OTTHUMP00000123426; PP2C; PP2C gamma; PP2C-gamma; PP2CG; PP2Cgamma; PPM1G; PPM1G_HUMAN; PPP2CG; Protein phosphatase 1C; Protein phosphatase 1G; Protein phosphatase 2 catalytic subunit gamma isoform; Protein phosphatase 2C gamma isoform ; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium dependent 1 gamma; Protein phosphatase magnesium-dependent 1 gamma; Protein phosphatase Mg2+/Mn2+ dependent 1G
Target Background
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
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