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The antibody against PRPF18 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human PRPF18 (NP_003666.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PRPF18 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human PRPF18 (NP_003666.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03257A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PRPF18 |
| Target Synonyms | PRP18; hPrp18; PRPF18 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human PRPF18 (NP_003666.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q99633 | Immunogen Sequence |
Uniprot Id
Q99633
Target Species
Human
Target Name
PRPF18
Target Full Name
Pre-mRNA-splicing factor 18
Target Function
Participates in the second step of pre-mRNA splicing.
Target Subcellular Location
Nucleus speckle.
Target Protein Families
PRP18 family
Target Synonyms
PRPF18; HPRP18Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18
Target Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18.
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