Rabbit anti-Human PRPF6 Polyclonal Antibody

The antibody against PRPF6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 592-941 of human PRPF6 (NP_036601.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05993A

Number

Cat.No	ADA-05993A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PRPF6
Target Synonyms	TOM; ANT1; Prp6; RP60; ANT-1; hPrp6; U5-102K; C20orf14; SNRNP102; PRPF6	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HT-29	Application	ELISA, WB

Cat.No

ADA-05993A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PRPF6

Target Synonyms

TOM; ANT1; Prp6; RP60; ANT-1; hPrp6; U5-102K; C20orf14; SNRNP102; PRPF6

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HT-29

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 592-941 of human PRPF6 (NP_036601.2).	Target Species	Human
Uniprot ID	O94906	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 592-941 of human PRPF6 (NP_036601.2).

Target Species

Human

Uniprot ID

O94906

Immunogen Sequence

Background Information

Uniprot Id

O94906
Target Species

Human
Target Name

PRPF6
Target Full Name

Pre-mRNA-processing factor 6
Target Function

Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
Target Involvement

Retinitis pigmentosa 60 (RP60)
Target Subcellular Location

Nucleus, nucleoplasm. Nucleus speckle.
Target Tissue Specificity

Widely expressed.
Target Synonyms

Androgen receptor N terminal domain transactivating protein 1; ANT 1; ANT1; C20orf14; hPrp6; p102 U5 small nuclear ribonucleoprotein particle binding protein; pre-mRNA processing factor 6; Pre-mRNA-processing factor 6; PRP6 homolog; PRP6 pre mRNA processing factor 6 homolog; PRP6_HUMAN; PRPF6; Putative mitochondrial outer membrane protein import receptor; TOM; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein; U5-102K
Target Background

The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.

Rabbit anti-Human PRPF6 Polyclonal Antibody

Specifications

Immunogen Information

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