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The antibody against PTGR3/ZADH2 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 33-371 of human PTGR3/ZADH2(NP_787103.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against PTGR3/ZADH2 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 33-371 of human PTGR3/ZADH2(NP_787103.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-08366A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PTGR3/ZADH2 |
| Target Synonyms | PRG-3; ZADH2; PTGR-3; PTGR3/ZADH2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse liver, Rat liver | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant Protein corresponding to a sequence within amino acids 33-371 of human PTGR3/ZADH2(NP_787103.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8N4Q0 | Immunogen Sequence |
Uniprot Id
Q8N4Q0
Target Species
Human
Target Name
PTGR3
Target Full Name
Prostaglandin reductase 3
Target Function
Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.
Target Subcellular Location
Peroxisome.
Target Protein Families
Zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily
Target Synonyms
ZADH2; PTGR3; Prostaglandin reductase 3; PRG-3; EC 1.3.1.48; Zinc-binding alcohol dehydrogenase domain-containing protein 2
Target Background
Predicted to enable 13-prostaglandin reductase activity. Predicted to be involved in negative regulation of fat cell differentiation. Predicted to be located in peroxisome.
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