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Rabbit anti-Human PTPRU Polyclonal Antibody

The antibody against PTPRU was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRU (NP_005695.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01299A

The antibody against PTPRU was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRU (NP_005695.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01299A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePTPRU
Target SynonymsFMI; PTP; PCP-2; PTP-J; PTPRO; PTPU2; PTP-PI; PTP-RO; PTPPSI; hPTP-J; R-PTP-U; R-PTP-PSI; PTPRUFormLiquid
Species ReactivityMouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human PTPRU (NP_005695.3).Target SpeciesHuman
Immunogen SequenceMARAQALVLALTFQLCAPETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVUniprot IDQ92729
Background Information
  • Uniprot Id

    Q92729

  • Target Species

    Human

  • Target Name

    PTPRU

  • Target Full Name

    Receptor-type tyrosine-protein phosphatase U

  • Target Function

    Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis.

  • Target Subcellular Location

    Cell junction. Cell membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Protein-tyrosine phosphatase family, Receptor class 2B subfamily

  • Target Tissue Specificity

    High levels in brain, pancreas, and skeletal muscle; less in colon, kidney, liver, stomach, and uterus; not expressed in placenta and spleen. Also detected in heart, prostate, lung, thymus, testis and ovary. Ubiquitously expressed in brain. Expressed by h

  • Target Synonyms

    PTPRU; FMI; PCP2; PTPRO; Receptor-type tyrosine-protein phosphatase U; R-PTP-U; EC 3.1.3.48; Pancreatic carcinoma phosphatase 2; PCP-2; Protein-tyrosine phosphatase J; PTP-J; hPTP-J; Protein-tyrosine phosphatase pi; PTP pi; Protein-tyrosine phosphatase receptor omicron; PTP-RO; Receptor-type protein-tyrosine phosphatase psi; R-PTP-psi

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