Rabbit anti-Human RASSF2 Polyclonal Antibody

The antibody against RASSF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 70-160 of human RASSF2 (NP_055552.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04851A

Number

Cat.No	ADA-04851A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	RASSF2
Target Synonyms	CENP-34; RASFADIN; RASSF2	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse lung, Rat lung	Application	ELISA, WB

Cat.No

ADA-04851A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

RASSF2

Target Synonyms

CENP-34; RASFADIN; RASSF2

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse lung, Rat lung

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 70-160 of human RASSF2 (NP_055552.1).	Target Species	Human
Immunogen Sequence	MQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQMPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSD	Uniprot ID	P50749

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 70-160 of human RASSF2 (NP_055552.1).

Target Species

Human

Immunogen Sequence

MQDDNERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPKVQISEVDAPPEGDQMPSSTDSRGLKPLQEDTPQLMRTRSDVGVRRRGNVRTPSD

Uniprot ID

P50749

Background Information

Uniprot Id

P50749
Target Species

Human
Target Name

RASSF2
Target Full Name

Ras association domain-containing protein 2
Target Function

Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Target Subcellular Location

Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1.
Target Tissue Specificity

Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
Target Synonyms

CENP 34; Centromere protein 34; Ras association (RalGDS/AF 6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain containing protein 2; Ras association domain-containing protein 2; RASF2_HUMAN; RASFADIN; RASSF2; RP4-599I11.1
Target Background

This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported.

Rabbit anti-Human RASSF2 Polyclonal Antibody

Specifications

Immunogen Information

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