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The antibody against RIT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human RIT2 (NP_002921.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RIT2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human RIT2 (NP_002921.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03391A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RIT2 |
| Target Synonyms | RIN; RIBA; ROC2; RIT2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-217 of human RIT2 (NP_002921.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q99578 | Immunogen Sequence |
Uniprot Id
Q99578
Target Species
Human
Target Name
RIT2
Target Full Name
GTP-binding protein Rit2
Target Function
Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.
Target Subcellular Location
Nucleus. Cell membrane.
Target Protein Families
Small GTPase superfamily, Ras family
Target Tissue Specificity
Neuron-specific.
Target Synonyms
GTP binding protein Rit2; GTP binding protein Roc2; GTP-binding protein Rit2; Ras like protein expressed in neurons; Ras like without CAAX 2; Ras like without CAAX protein 2; Ras-like protein expressed in neurons; Ras-like without CAAX protein 2; RIBA; Ric (Drosophila) like; Ric like; Ric like, expressed in neurons; RIN; RIT2; RIT2_HUMAN; ROC2
Target Background
RIN belongs to the RAS (HRAS; MIM 190020) superfamily of small GTPases (Shao et al., 1999 [PubMed 10545207]).
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