Rabbit anti-Human S1PR4 Polyclonal Antibody

The antibody against S1PR4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human S1PR4 (NP_003766.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05264A

Number

Cat.No	ADA-05264A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	S1PR4
Target Synonyms	EDG6; LPC1; S1P4; SLP4; S1PR4	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549, Jurkat, Raji	Application	ELISA, WB

Cat.No

ADA-05264A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

S1PR4

Target Synonyms

EDG6; LPC1; S1P4; SLP4; S1PR4

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549, Jurkat, Raji

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human S1PR4 (NP_003766.1).	Target Species	Human
Immunogen Sequence	SAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI	Uniprot ID	O95977

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human S1PR4 (NP_003766.1).

Target Species

Human

Immunogen Sequence

SAVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDSFRGSRSLSFRMREPLSSISSVRSI

Uniprot ID

O95977

Background Information

Uniprot Id

O95977
Target Species

Human
Target Name

S1PR4
Target Full Name

Sphingosine 1-phosphate receptor 4
Target Function

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 1 family
Target Tissue Specificity

Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone
Target Synonyms

S1PR4; EDG6; Sphingosine 1-phosphate receptor 4; S1P receptor 4; S1P4; Endothelial differentiation G-protein coupled receptor 6; Sphingosine 1-phosphate receptor Edg-6; S1P receptor Edg-6
Target Background

This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.

Rabbit anti-Human S1PR4 Polyclonal Antibody

Specifications

Immunogen Information

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