Rabbit anti-Human SEPSECS Polyclonal Antibody

The antibody against SEPSECS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 222-501 of human SEPSECS (NP_058651.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-09377A

Number

Cat.No	ADA-09377A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SEPSECS
Target Synonyms	LP; SLA; SecS; PCH2D; SLA/LP; SLA-p35; SEPSECS	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, 293T, Rat liver, THP-1	Application	ELISA, WB, IF/ICC

Cat.No

ADA-09377A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SEPSECS

Target Synonyms

LP; SLA; SecS; PCH2D; SLA/LP; SLA-p35; SEPSECS

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, 293T, Rat liver, THP-1

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 222-501 of human SEPSECS (NP_058651.3).	Target Species	Human
Uniprot ID	Q9HD40	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 222-501 of human SEPSECS (NP_058651.3).

Target Species

Human

Uniprot ID

Q9HD40

Immunogen Sequence

Background Information

Uniprot Id

Q9HD40
Target Species

Human
Target Name

SEPSECS
Target Full Name

O-phosphoseryl-tRNA(Sec) selenium transferase
Target Function

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
Target Involvement

Pontocerebellar hypoplasia 2D (PCH2D)
Target Subcellular Location

Cytoplasm.
Target Protein Families

SepSecS family
Target Tissue Specificity

Primarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells.
Target Research Area

Epigenetics and Nuclear Signaling, Metabolism
Target Synonyms

DKFZp434B1417; Liver pancreas antigen; Liver-pancreas antigen; LP; MGC161491; O phosphoseryl tRNA(Sec) selenium transferase; O-phosphoseryl-tRNA(Sec) selenium transferase; Sec synthase; Selenocysteine synthase; Selenocysteinyl tRNA(Sec) synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep (O phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase; Sep tRNA:Sec tRNA synthase; Sep-tRNA:Sec-tRNA synthase; SepSecS; SLA; SLA p35; SLA-p35; SLA/LP; SLA/LP autoantigen; Soluble liver antigen; Soluble liver antigen/liver pancreas antigen; Soluble Liver/Pancreas Antigen; SPCS_HUMAN; tRNA(Ser/Sec) associated antigenic protein; tRNA(Ser/Sec)-associated antigenic protein; TRNP48; UGA suppressor tRNA associated protein; UGA suppressor tRNA-associated protein
Target Background

The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).

Rabbit anti-Human SEPSECS Polyclonal Antibody

Specifications

Immunogen Information

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