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The antibody against SLC3A1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 416-685 of human SLC3A1 (NP_000332.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against SLC3A1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 416-685 of human SLC3A1 (NP_000332.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-09679A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC3A1 |
| Target Synonyms | D2H; ATR1; NBAT; RBAT; CSNU1; SLC3A1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, BxPC-3, HepG2, HT-29, Mouse liver, PC-12 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 416-685 of human SLC3A1 (NP_000332.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q07837 | Immunogen Sequence |
Uniprot Id
Q07837
Target Species
Human
Target Name
SLC3A1
Target Full Name
Amino acid transporter heavy chain SLC3A1
Target Function
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule.
Target Involvement
Cystinuria (CSNU); Hypotonia-cystinuria syndrome (HCS)
Target Subcellular Location
Membrane; Single-pass type II membrane protein.
Target Tissue Specificity
Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver.
Target Synonyms
D2H; ATR1; NBAT; RBAT; CSNU1; SLC3A1
Target Background
This gene encodes a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract. Mutations and deletions in this gene are associated with cystinuria. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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