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The antibody against SMNDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human SMNDC1 (NP_005862.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SMNDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human SMNDC1 (NP_005862.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06512A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SMNDC1 |
| Target Synonyms | SMNR; SPF30; TDRD16C; SMNDC1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HT-1080, Jurkat, Mouse thymus, PC-12, Rat thymus, SH-SY5Y, SKOV3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-238 of human SMNDC1 (NP_005862.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O75940 | Immunogen Sequence |
Uniprot Id
O75940
Target Species
Human
Target Name
SMNDC1
Target Full Name
Survival of motor neuron-related-splicing factor 30
Target Function
Involved in spliceosome assembly.
Target Subcellular Location
Nucleus speckle. Nucleus, Cajal body.
Target Protein Families
SMN family
Target Tissue Specificity
Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.
Target Synonyms
30 kDa splicing factor SMNrp; MGC106917; MGC112663; SMN related protein; SMN-related protein; smndc1; SMNR; SPF30; SPF30_HUMAN; Splicing factor 30, survival of motor neuron-related; Survival motor neuron domain containing 1; Survival motor neuron domain containing protein 1; Survival motor neuron domain-containing protein 1; Survival of motor neuron related splicing factor 30; Survival of motor neuron-related-splicing factor 30
Target Background
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
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