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The antibody against SMU1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SMU1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01046A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SMU1 |
| Target Synonyms | BWD; SMU-1; fSAP57; SMU1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-431, HT-29, Mouse intestine, Mouse liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SMU1 (NP_060695.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q2TAY7 | Immunogen Sequence |
Uniprot Id
Q2TAY7
Target Species
Human
Target Name
SMU1
Target Full Name
WD40 repeat-containing protein SMU1
Target Function
Involved in pre-mRNA splicing as a component of the spliceosome. Regulates alternative splicing of the HSPG2 pre-mRNA. Required for normal accumulation of IK. Required for normal mitotic spindle assembly and normal progress through mitosis.; (Microbial infection) Required, together with IK, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
Target Subcellular Location
Cytoplasm. Nucleus. Nucleus speckle.
Target Protein Families
WD repeat SMU1 family
Target Synonyms
SMU1; WD40 repeat-containing protein SMU1; Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1; N-terminally processed]
Target Background
Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type precatalytic spliceosome.
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