Rabbit anti-Human SNX4 Monoclonal Antibody

The antibody against SNX4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 321-400 of human SNX4 (NP_003785.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

ADA-14519A

Number

Cat.No	ADA-14519A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	SNX4
Target Synonyms	ATG24B; SNX4	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Mouse heart, NIH/3T3, Jurkat	Application	ELISA, WB, IP

Cat.No

ADA-14519A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

SNX4

Target Synonyms

ATG24B; SNX4

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Mouse heart, NIH/3T3, Jurkat

Application

ELISA, WB, IP

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 321-400 of human SNX4 (NP_003785.1).	Target Species	Human
Immunogen Sequence	HELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFV	Uniprot ID	O95219

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 321-400 of human SNX4 (NP_003785.1).

Target Species

Human

Immunogen Sequence

HELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLEEQINEGEQQLKSKNLEGREFV

Uniprot ID

O95219

Background Information

Uniprot Id

O95219
Target Species

Human
Target Name

SNX4
Target Full Name

Sorting nexin-4
Target Function

Involved in the regulation of endocytosis and in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A.
Target Subcellular Location

Early endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families

Sorting nexin family
Target Synonyms

ATG24B; SNX 4; snx4; SNX4_HUMAN; Sorting nexin 4; Sorting nexin-4
Target Background

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene.

Rabbit anti-Human SNX4 Monoclonal Antibody

Specifications

Immunogen Information

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