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The antibody against SRD5A1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SRD5A1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11408A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRD5A1 |
| Target Synonyms | S5AR 1; SRD5A1 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse skin | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | LIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYF | Uniprot ID | P18405 |
Uniprot Id
P18405
Target Species
Human
Target Name
SRD5A1
Target Full Name
3-oxo-5-alpha-steroid 4-dehydrogenase 1
Target Function
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Target Subcellular Location
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Steroid 5-alpha reductase family
Target Tissue Specificity
Liver and prostate (at a low level).
Target Research Area
Neuroscience
Target Synonyms
SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; SR type 1; Steroid 5-alpha-reductase 1; S5AR 1
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