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Rabbit anti-Human SRD5A1 Polyclonal Antibody

The antibody against SRD5A1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11408A

The antibody against SRD5A1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-11408A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSRD5A1
Target SynonymsS5AR 1; SRD5A1FormLiquid
Species ReactivityMouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse skinApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1).Target SpeciesHuman
Immunogen SequenceLIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFUniprot IDP18405
Background Information
  • Uniprot Id

    P18405

  • Target Species

    Human

  • Target Name

    SRD5A1

  • Target Full Name

    3-oxo-5-alpha-steroid 4-dehydrogenase 1

  • Target Function

    Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

  • Target Subcellular Location

    Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    Steroid 5-alpha reductase family

  • Target Tissue Specificity

    Liver and prostate (at a low level).

  • Target Research Area

    Neuroscience

  • Target Synonyms

    SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; SR type 1; Steroid 5-alpha-reductase 1; S5AR 1

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