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The antibody against TBL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-430 of human TBL2 (NP_036585.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TBL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 100-430 of human TBL2 (NP_036585.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05067A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TBL2 |
| Target Synonyms | WBSCR13; WS-betaTRP; TBL2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 293T, LO2, Mouse brain, Rat pancreas | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 100-430 of human TBL2 (NP_036585.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y4P3 | Immunogen Sequence |
Uniprot Id
Q9Y4P3
Target Species
Human
Target Name
TBL2
Target Full Name
Transducin beta-like protein 2
Target Involvement
TBL2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of TBL2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
Target Synonyms
TBL2; WBSCR13; UNQ563/PRO1125Transducin beta-like protein 2; WS beta-transducin repeats protein; WS-betaTRP; Williams-Beuren syndrome chromosomal region 13 protein
Target Background
This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
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