Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against TGM3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human TGM3 (NP_003236.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against TGM3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human TGM3 (NP_003236.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-08241A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TGM3 |
| Target Synonyms | TGM3; TGE; UHS2; transglutaminase 3 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, 293T-TGM35-His(C) | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human TGM3 (NP_003236.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | SRVITNFNSAHDTDRNLSVDVYYDPMGNPLDKGSDSVWNFHVWNEGWFVRSDLGPSYGGWQVLDATPQERSQGVFQCGPASVIGVREGDVQLNFDMPFIFAEVNADRITWLYDNTTGKQWKNSVNSHTIGRYISTKAVGSNARMDVTDKYKYPEGSDQERQVFQKALGKLKPNTPFAATSSMGLETEEQE | Uniprot ID | Q08188 |
Uniprot Id
Q08188
Target Species
Human
Target Name
TGM3
Target Full Name
Protein-glutamine gamma-glutamyltransferase E
Target Function
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold. In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath
Target Involvement
Uncombable hair syndrome 2 (UHS2)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Transglutaminase superfamily, Transglutaminase family
Target Synonyms
E polypeptide protein glutamine gamma glutamyltransferase; MGC126249; MGC126250; Protein glutamine gamma glutamyltransferase E 27 kDa catalytic chain; Protein glutamine gamma glutamyltransferase E 50 kDa noncatalytic chain; Protein glutamine gamma glutamyltransferase E; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain; TG(E); TGase E; TGase-3; TGE; TGM 3; TGM3; TGM3_HUMAN; Transglutaminase E; Transglutaminase-3; Transglutaminase3; TransglutaminaseE
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
