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The antibody against TKFC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 226-575 of human TKFC (NP_056348.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against TKFC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 226-575 of human TKFC (NP_056348.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00597A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | TKFC |
| Target Synonyms | DAK; NET45; TKFCD; TKFC | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart, 293T, LO2, Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 226-575 of human TKFC (NP_056348.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q3LXA3 | Immunogen Sequence |
Uniprot Id
Q3LXA3
Target Species
Human
Target Name
TKFC
Target Full Name
Triokinase/FMN cyclase
Target Function
Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.
Target Protein Families
Dihydroxyacetone kinase (DAK) family
Target Tissue Specificity
Detected in erythrocytes (at protein level).
Target Synonyms
ATP dependent dihydroxyacetone kinase; Bifunctional ATP dependent dihydroxyacetone kinase/FAD AMP lyase (cyclizing); DAK; DHA kinase; Dha kinase/FMN cyclase; DHAK_HUMAN; Dihydroxyacetone kinase; Dihydroxyacetone kinase 2; Dihydroxyacetone kinase 2 homolog (S. cerevisiae); Dihydroxyacetone kinase 2 homolog (yeast); FAD AMP lyase (cyclic FMN forming); FAD AMP lyase (cyclizing); FAD-AMP lyase (cyclic FMN forming); FAD-AMP lyase (cyclizing); FMN cyclase; Glycerone kinase
Target Background
This gene is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4', 5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been found for this gene.
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