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Rabbit anti-Human TPK1 Polyclonal Antibody

The antibody against TPK1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human TPK1 (NP_071890.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03918A

The antibody against TPK1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human TPK1 (NP_071890.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03918A ClonalityPolyclonal
Host SpeciesRabbitTarget NameTPK1
Target SynonymsPP20; HTPK1; THMD5; TPK1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, Rat kidneyApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-243 of human TPK1 (NP_071890.2).Target SpeciesHuman
Uniprot IDQ9H3S4Immunogen Sequence
Background Information
  • Uniprot Id

    Q9H3S4

  • Target Species

    Human

  • Target Name

    TPK1

  • Target Full Name

    Thiamine pyrophosphokinase 1

  • Target Function

    Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.

  • Target Involvement

    Thiamine metabolism dysfunction syndrome 5, episodic encephalopathy type (THMD5)

  • Target Protein Families

    Thiamine pyrophosphokinase family

  • Target Tissue Specificity

    Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues.

  • Target Research Area

    others

  • Target Synonyms

    hTPK1; Placental protein 20; PP20; Thiamin pyrophosphokinase 1; Thiamine diphosphokinase; Thiamine kinase; Thiamine pyrophosphokinase 1; THMD5; TPK1; TPK1_HUMAN

  • Target Background

    The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5.

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