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The antibody against UFC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human UFC1 (NP_057490.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against UFC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human UFC1 (NP_057490.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-03500A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | UFC1 |
| Target Synonyms | NEDSG; HSPC155; UFC1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-549, Mouse brain, U-87MG | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-167 of human UFC1 (NP_057490.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MADEATRRVVSEIPVLKTNAGPRDRELWVQRLKEEYQSLIRYVENNKNADNDWFRLESNKEGTRWFGKCWYIHDLLKYEFDIEFDIPITYPTTAPEIAVPELDGKTAKMYRGGKICLTDHFKPLWARNVPKFGLAHLMALGLGPWLAVEIPDLIQKGVIQHKEKCNQ | Uniprot ID | Q9Y3C8 |
Uniprot Id
Q9Y3C8
Target Species
Human
Target Name
UFC1
Target Full Name
Ubiquitin-fold modifier-conjugating enzyme 1
Target Function
E1-like enzyme which specifically catalyzes the second step in ufmylation. Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
Target Protein Families
Ubiquitin-conjugating enzyme family, UFC1 subfamily
Target Synonyms
CGI-126; HSPC155; Ubiquitin fold modifier conjugating enzyme 1; Ubiquitin-fold modifier-conjugating enzyme 1; UFC1; UFC1_HUMAN; Ufm1 conjugating enzyme 1; Ufm1-conjugating enzyme 1
Target Background
UFC1 is an E2-like conjugating enzyme for ubiquitin-fold modifier-1 (UFM1; MIM 610553) (Komatsu et al., 2004 [PubMed 15071506]).
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