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The antibody against USF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human USF1 (NP_009053.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against USF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human USF1 (NP_009053.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-10300A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | USF1 |
| Target Synonyms | UEF; FCHL; MLTF; FCHL1; MLTFI; HYPLIP1; bHLHb11; USF1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse spleen | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human USF1 (NP_009053.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P22415 | Immunogen Sequence |
Uniprot Id
P22415
Target Species
Human
Target Name
USF1
Target Full Name
Upstream stimulatory factor 1
Target Function
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Target Involvement
Hyperlipidemia combined 1 (HYPLIP1)
Target Subcellular Location
Nucleus.
Target Research Area
Transcription
Target Synonyms
USF1; BHLHB11; USF; Upstream stimulatory factor 1; Class B basic helix-loop-helix protein 11; bHLHb11; Major late transcription factor 1
Target Background
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21.
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