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The antibody against VDAC3 was raised in rabbit using the Recombinant Human Voltage-dependent anion-selective channel protein 3 protein (40-160aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against VDAC3 was raised in rabbit using the Recombinant Human Voltage-dependent anion-selective channel protein 3 protein (40-160aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
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Western Blot | Positive WB detected in: K562 whole cell lysate,A549 whole cell lysate,293 whole cell lysate,U251 whole cell lysate,HL-60 whole cell lysate,Hela whole cell lysate | All lanes: VDAC3 antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 31 kDa | Observed band size: 32 kDa
| Cat.No | ADC-54879A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VDAC3 |
| Target Synonyms | VDAC3, Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3) | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Voltage-dependent anion-selective channel protein 3 protein (40-160aa) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y277 |
Uniprot Id
Q9Y277
Target Species
Human
Target Name
VDAC3
Target Full Name
Non-selective voltage-gated ion channel VDAC3
Target Function
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
Target Subcellular Location
Mitochondrion outer membrane. Membrane.
Target Protein Families
Eukaryotic mitochondrial porin family
Target Tissue Specificity
Expressed in erythrocytes (at protein level). Widely expressed. Highest in testis.
Target Synonyms
VDAC3; Voltage-dependent anion-selective channel protein 3; VDAC-3; hVDAC3; Outer mitochondrial membrane protein porin 3
Target Background
This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.
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