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The antibody against VEPH1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 448-547 of human VEPH1 (NP_078897.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against VEPH1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 448-547 of human VEPH1 (NP_078897.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05200A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VEPH1 |
| Target Synonyms | MELT; VEPH; VEPH1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-431 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 448-547 of human VEPH1 (NP_078897.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | KSLAFHTMLTKGVGSDDGEDENRGDIPASISLSEIDPLGQGNDKLPFKTDTERSQLGESSVSYPNIIHIDSENLSETVKENSQEETPETTASPIEYQDKL | Uniprot ID | Q14D04 |
Uniprot Id
Q14D04
Target Species
Human
Target Name
VEPH1
Target Full Name
Ventricular zone-expressed PH domain-containing protein homolog 1
Target Function
Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.
Target Subcellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
MELT/VEPH family
Target Synonyms
2810471M23Rik; MELT; MELT_HUMAN; Protein melted; RGD1308217; Ventricular zone-expressed PH domain-containing protein homolog 1; VEPH; Veph1
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