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The antibody against WNT3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 166-355 of human WNT3 (NP_110380.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against WNT3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 166-355 of human WNT3 (NP_110380.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11701A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Wnt3 |
| Target Synonyms | INT4; TETAMS; WNT3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549, K-562, SGC-7901, SKOV3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 166-355 of human WNT3 (NP_110380.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | VLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYSLFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIRIYDVHTCK | Uniprot ID | P56703 |
Uniprot Id
P56703
Target Species
Human
Target Name
WNT3
Target Full Name
Proto-oncogene Wnt-3
Target Function
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge. Required for normal embryonic development, and especially for limb development.
Target Involvement
Tetraamelia syndrome, autosomal recessive (TETAMS)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix. Secreted.
Target Protein Families
Wnt family
Target Synonyms
Int 4; INT4; MGC131950; MGC138321; MGC138323; Proto-oncogene Int-4 homolog; Proto-oncogene Wnt-3; wingless type MMTV integration site family member 3; Wnt 3 proto oncogene protein; WNT 3 proto oncogene protein precursor; wnt3; WNT3_HUMAN
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