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The antibody against WSB1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 182-421 of human WSB1 (NP_056441.6) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against WSB1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 182-421 of human WSB1 (NP_056441.6) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02233A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | WSB1 |
| Target Synonyms | SWIP1; WSB-1; WSB1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-549, HepG2, HT-29, SGC-7901 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 182-421 of human WSB1 (NP_056441.6). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y6I7 | Immunogen Sequence |
Uniprot Id
Q9Y6I7
Target Species
Human
Target Name
WSB1
Target Full Name
WD repeat and SOCS box-containing protein 1
Target Function
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.
Target Synonyms
WSB1; SWIP1; WD repeat and SOCS box-containing protein 1; WSB-1; SOCS box-containing WD protein SWiP-1
Target Background
This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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