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The antibody against ZFX was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ZFX (NP_003401.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ZFX was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ZFX (NP_003401.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-08739A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ZFX |
| Target Synonyms | ZNF926; ZFX | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | H460, HL-60, Mouse lung, Mouse spleen, Mouse testis, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ZFX (NP_003401.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P17010 | Immunogen Sequence |
Uniprot Id
P17010
Target Species
Human
Target Name
ZFX
Target Full Name
Zinc finger X-chromosomal protein
Target Function
Probable transcriptional activator.
Target Subcellular Location
Nucleus.
Target Protein Families
Krueppel C2H2-type zinc-finger protein family, ZFX/ZFY subfamily
Target Synonyms
X-linked zinc finger protein; zfx; ZFX_HUMAN; Zinc finger protein, X-linked; Zinc Finger X Chromosomal Protein; Zinc finger X-chromosomal protein; ZNF926
Target Background
This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.
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