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The antibody against DR5/TRAILR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 53-170 of mouse DR5/TRAILR2( NP_064671.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on FC, ELISA.
The antibody against DR5/TRAILR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 53-170 of mouse DR5/TRAILR2( NP_064671.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on FC, ELISA.
Flow cytometry: 1X10^6 293F cells (negative control, left)?and 293F (Transfection, right) cells were surface-stained with DR5/TRAILR2 Rabbit mAb or ABflo? 647 Rabbit IgG isotype control, followed by Alexa Fluor? 647 conjugated goat anti-rabbit pAb staining. Non-fluorescently stained cells were used as blank control (red line).
| Cat.No | ADA-15703A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DR5/TRAILR2 |
| Target Synonyms | MK; DR5; Ly98; KILLER; TRICKB; TRAILR2; TRICK2A; TRICK2B | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, FC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 53-170 of mouse DR5/TRAILR2( NP_064671.2). | Target Species | Mouse |
|---|---|---|---|
| Immunogen Sequence | NPAHNRPAGLQRPEESPSRGPCLAGQYLSEGNCKPCREGIDYTSHSNHSLDSCILCTVCKEDKVVETRCNITTNTVCRCKPGTFEDKDSPEICQSCSNCTDGEEELTSCTPRENRKCV | Uniprot ID | Q9QZM4 |
Uniprot Id
Q9QZM4
Target Synonyms
MK; DR5; Ly98; KILLER; TRICKB; TRAILR2; TRICK2A; TRICK2B
Target Background
Predicted to enable TRAIL receptor activity; identical protein binding activity; and protease binding activity. Predicted to be involved in TRAIL-activated apoptotic signaling pathway and positive regulation of apoptotic process. Predicted to act upstream of or within apoptotic process and regulation of apoptotic process. Predicted to be located in Golgi apparatus; cytosol; and membrane raft. Predicted to be active in cell surface and plasma membrane. Is expressed in bladder; liver; renal vasculature; urethra of female; and urethra of male. Human ortholog(s) of this gene implicated in carcinoma (multiple); cervical cancer; hematologic cancer (multiple); and urinary bladder cancer. Orthologous to several human genes including TNFRSF10A (TNF receptor superfamily member 10a).
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