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The antibody against RIP3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 320-420 of mouse RIP3(NP_064339.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IHC-P, IF/ICC, ELISA.
The antibody against RIP3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 320-420 of mouse RIP3(NP_064339.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IHC-P, IF/ICC, ELISA.
Immunohistochemistry analysis of?RIP3 in paraffin-embedded?rat kidney tissue using?RIP3 Rabbit pAb at a dilution of 1:100 (40x lens).?High pressure antigen retrieval was performed with 0.01 M citrate buffer (pH 6.0) prior to IHC staining.
| Cat.No | ADA-08382A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RIP3 |
| Target Synonyms | Rip3; 2610528K09Rik; RIP3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, IF/ICC, IHC-P |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 320-420 of mouse RIP3(NP_064339.2). | Target Species | Mouse |
|---|---|---|---|
| Immunogen Sequence | LSAREPSQRGTEMDCPRETMVSKMLDRLHLEEPSGPVPGKCPERQAQDTSVGPATPARTSSDPVAGTPQIPHTLPFRGTTPGPVFTETPGPHPQRNQGDGR | Uniprot ID | Q9QZL0 |
Uniprot Id
Q9QZL0
Target Synonyms
Rip3; 2610528K09Rik; RIP3
Target Background
Enables NF-kappaB-inducing kinase activity and protein serine/threonine kinase activity. Involved in several processes, including execution phase of necroptosis; hematopoietic or lymphoid organ development; and regulation of programmed cell death. Acts upstream of or within several processes, including I-kappaB kinase/NF-kappaB signaling; positive regulation of intrinsic apoptotic signaling pathway; and positive regulation of protein deacetylation. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; hemolymphoid system gland; male reproductive gland or organ; primitive streak; and turbinate bone primordium. Orthologous to human RIPK3 (receptor interacting serine/threonine kinase 3).
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