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The antibody against Early E3 18.5 kDa glycoprotein was raised in rabbit using the Recombinant Human adenovirus C serotype 5 Early E3 18.5 kDa glycoprotein protein (18-124aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
The antibody against Early E3 18.5 kDa glycoprotein was raised in rabbit using the Recombinant Human adenovirus C serotype 5 Early E3 18.5 kDa glycoprotein protein (18-124aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: recombinant protein | All lanes: Early E3 18.5 kDa glycoprotein Antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 30 kDa | Observed band size: 30 kDa
| Cat.No | ADC-54645A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Early E3 18.5 kDa glycoprotein |
| Target Synonyms | Early E3 18.5 kDa glycoprotein (E3-19K) (E3gp 19 kDa) (E19) (GP19K) | Form | Liquid |
| Species Reactivity | Human adenovirus C serotype 5 | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Affinity-chromatography purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human adenovirus C serotype 5 Early E3 18.5 kDa glycoprotein protein (18-124aa) | Target Species | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04494 |
Uniprot Id
P04494
Target Species
Human adenovirus C serotype 5
Target Function
Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface. Also delays the expression of class I alleles that it cannot affect by direct retention. Binds transporters associated with antigen processing (TAP) and acts as a tapasin inhibitor, preventing class I/TAP association. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
Target Subcellular Location
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Target Protein Families
Adenoviridae E19 family
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