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Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1), Truncated

ACP17397

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17397 Target NamePLCH1
Target Synonyms1-phosphatidylinositol 4; 1-phosphatidylinositol-4; 1-phosphatidylinositol-4FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ4KWH8
Background Information
  • Uniprot Id

    Q4KWH8

  • Target Species

    Human

  • Target Name

    PLCH1

  • Target Full Name

    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

  • Target Function

    The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes.

  • Target Subcellular Location

    Cytoplasm. Membrane.

  • Target Tissue Specificity

    Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord.

  • Target Synonyms

    1-phosphatidylinositol 4; 1-phosphatidylinositol-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1; 5-bisphosphate phosphodiesterase eta-1; DKFZp434C1372; KIAA1069; MGC117152; Phosphoinositide phospholipase C-eta-1; Phospholipase C-eta-1; Phospholipase C-like protein 3; PLC-eta-1; PLC-L3; PLCeta1; Plch1; PLCH1_HUMAN; PLCL3

  • Target Background

    PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4, 5-bisphosphate (PtdIns(4, 5)P2) to generate second messengers inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).

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