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| Cat.No | ACP08729 | Target Name | TYRP1 |
|---|---|---|---|
| Target Synonyms | 6-dihydroxyindole-2-carboxylic acid oxidase; DHICA oxidase; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1; TRP; TRP-1; TRP1, TYRP1; CAS2; TYRP; TYRRP; 5 | Form | Liquid or Lyophilized powder |
| Expression System | Mammalian cell | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P17643 |
|---|
Uniprot Id
P17643
Target Species
Human
Target Name
TYRP1
Target Full Name
5,6-dihydroxyindole-2-carboxylic acid oxidase
Target Function
Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions, but not in the presence of Zn(2+). May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.
Target Involvement
Albinism, oculocutaneous, 3 (OCA3)
Target Subcellular Location
Melanosome membrane; Single-pass type I membrane protein. Melanosome.
Target Protein Families
Tyrosinase family
Target Tissue Specificity
Pigment cells.
Target Synonyms
TYRP1; CAS2; TYRP; TYRRP; 5,6-dihydroxyindole-2-carboxylic acid oxidase; DHICA oxidase; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1; TRP; TRP-1; TRP1
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