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| Cat.No | ACP18888 | Target Name | ABT1 |
|---|---|---|---|
| Target Synonyms | ABT1; ABT1_HUMAN; Activator of basal transcription 1; Basal transcriptional activator 1; Basal transcriptional activator; hABT1; HGNC:17369; OTTHUMP00000017935; TATA-binding protein-binding protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-272 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9ULW3 |
|---|
Uniprot Id
Q9ULW3
Target Species
Human
Target Name
ABT1
Target Full Name
Activator of basal transcription 1
Target Function
Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes.
Target Subcellular Location
Nucleus. Nucleus, nucleolus.
Target Protein Families
ESF2/ABP1 family
Target Synonyms
ABT1; ABT1_HUMAN; Activator of basal transcription 1; Basal transcriptional activator 1; Basal transcriptional activator; hABT1; HGNC:17369; OTTHUMP00000017935; TATA-binding protein-binding protein
Target Background
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.
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