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Recombinant Human Activator of basal transcription 1 (ABT1)

ACP18888

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18888 Target NameABT1
Target SynonymsABT1; ABT1_HUMAN; Activator of basal transcription 1; Basal transcriptional activator 1; Basal transcriptional activator; hABT1; HGNC:17369; OTTHUMP00000017935; TATA-binding protein-binding proteinFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-272
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9ULW3
Background Information
  • Uniprot Id

    Q9ULW3

  • Target Species

    Human

  • Target Name

    ABT1

  • Target Full Name

    Activator of basal transcription 1

  • Target Function

    Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes.

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus.

  • Target Protein Families

    ESF2/ABP1 family

  • Target Synonyms

    ABT1; ABT1_HUMAN; Activator of basal transcription 1; Basal transcriptional activator 1; Basal transcriptional activator; hABT1; HGNC:17369; OTTHUMP00000017935; TATA-binding protein-binding protein

  • Target Background

    Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.

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