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| Cat.No | ACP13063 | Target Name | ARRDC4 |
|---|---|---|---|
| Target Synonyms | ARRD4_HUMAN; ARRDC 4; Arrdc4; Arrestin domain containing protein 4; Arrestin domain-containing protein 4; FLJ36045 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-418 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NCT1 |
|---|
Uniprot Id
Q8NCT1
Target Species
Human
Target Name
ARRDC4
Target Full Name
Arrestin domain-containing protein 4
Target Function
Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism plays also a role in the incorporation of SLC11A2 into extracellular vesicles. May play a role in glucose uptake.
Target Subcellular Location
Early endosome. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle.
Target Protein Families
Arrestin family
Target Synonyms
ARRD4_HUMAN; ARRDC 4; Arrdc4; Arrestin domain containing protein 4; Arrestin domain-containing protein 4; FLJ36045
Target Background
Predicted to enable ubiquitin ligase-substrate adaptor activity. Acts upstream of or within positive regulation of ubiquitin-protein transferase activity. Located in endosome and plasma membrane.
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