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Recombinant Human Ataxin-7 (ATXN7), Truncated

ACP01958

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Specifications

Cat.No	ACP01958	Target Name	ATXN7
Target Synonyms	(Spinocerebellar ataxia type 7 protein)	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	79-401aa
Mol Weight	43.1 kDa	Protein Length	Partial
Purity	Greater than 85% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O15265

Background Information

Uniprot Id

O15265
Target Species

Human
Target Name

ATXN7
Target Full Name

Ataxin-7
Target Function

Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization.
Target Involvement

Spinocerebellar ataxia 7 (SCA7)
Target Subcellular Location

[Isoform a]: Nucleus. Nucleus, nucleolus. Nucleus matrix. Cytoplasm, cytoskeleton. Note=In addition to a diffuse distribution throughout the nucleus, it is associated with the nuclear matrix and the nucleolus. It is able to shuttle between the nucleus and cytoplasm.; [Isoform b]: Cytoplasm.
Target Protein Families

Ataxin-7 family
Target Tissue Specificity

Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymp
Target Research Area

Neuroscience
Target Synonyms

ATXN7; SCA7Ataxin-7; Spinocerebellar ataxia type 7 protein

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Recombinant Human Ataxin-7 (ATXN7), Truncated

Specifications

Immunogen Information

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